ZAYA: Next-Gen Birth Control

We believe birth control should work seamlessly with your body and your life—not disrupt it. That’s why we’re developing ZAYA, a first-in-class, once-weekly pill without hormones designed to provide effective, low-maintenance contraception without the side effects that often drive dissatisfaction and discontinuation.

We know that contraception isn’t just about preventing pregnancy; it’s about supporting your overall well-being. That’s why ZAYA is being designed not only for convenience and fewer side effects but also with the potential to help manage heavy and painful periods, endometriosis, and other reproductive health concerns. By reimagining what birth control can do, we're giving people more control, more choices, and more confidence in their bodies.

🌟 Ormeloxifene, our parent drug, is a Selective Estrogen Receptor Modulator (SERM)

🏆 It doesn’t have synthetic hormones or contraindications/risks common to hormonal options

🌍 Trusted by millions—women and gender diverse individuals have used ormeloxifene weekly for more than 30 years with a strong safety profile.

💊 Once-weekly dosing improves adherence—reducing the risk of missed pills compared to daily birth control.

ZAYA selectively targets uterine estrogen receptors, inhibiting the nidatory rush of estrogen, which takes egg & endometrial development out of sync (preventing pregnancy) without affecting:

Ovulation

HPA-axis

FSH/LH Levels

Breastfeeding

Libido

Weight

ZAYA has potential to be a treatment for:

Breast Cancer

Ovarian Cancer

& other chronic conditions

Endometriosis

Heavy/Painful Periods

Uterine Fibroids

ZAYA also helps with:

Mastalgia & Fibroadenomas

Lochia

Why hasn’t this been done before? After a failed attempt in the 90s, there hasn’t been much action to bring it through the FDA/EMA, because of its off-patent status. But, look out world, we’re coming through with an improved (& on-patent) version!

the literature